Kidney Disease Stages

Kidney disease is divided into 5 stages based on the level of kidney function. Your kidney disease stage is determined by calculating your estimated glomerular filtration rate (eGFR).

What is eGFR (estimated Glomerular Filtration Rate)?

The estimated Glomerular Filtration Rate (eGFR) is a measure of how well the kidneys clean blood. It is usually estimated based on blood test results and age and gender.

Kidney Disease Stage

 

What does it mean?

 

Possible signs and symptoms

 

eGFR

 

Stage 1

 

Kidney damage in the presence of normal kidney function

 

High blood pressure, leg swelling, urinary tract infection, abnormal urine test

 

90-120

 

Stage 2

 

Mild loss of kidney function

 

 

60-89

 

Stage 3

 

3a: Mild to moderate loss of kidney function;

 

Changes in urination, swelling of hands and feet, weakness or fatigue, dry itchy skin, back pain, muscle cramps

 

3a: 45-59

 

 

 

 

3b: Moderate to severe loss of kidney function

 

 

3b: 30-44

 

 

Stage 4

 

Severe loss of kidney function

 

Anemia, loss of appetite, bone disease, abnormal blood phosphorus, calcium, and vitamin D levels

 

15-29

 

Stage 5

 

Kidney failure or near failure

 

Uremia, fatigue, shortness of breath, nausea, vomiting, abnormal thyroid levels, swelling of hands/legs/eyes/waist, low back pain

 

Less than 15

 

What is early kidney disease? What is end-stage renal disease?

For simplicity, kidney disease stages 1 to 3a are called early kidney disease, while kidney disease stages 3b to 5 are called late kidney disease. 

The goal at every stage of kidney disease is to best care for and control your health so that you can help slow the progression of kidney disease and keep your kidneys working for as long as possible.

Understand the progression of kidney disease

Kidney disease is a progressive disease, which means your kidney function may decline over time. However, being diagnosed with early-stage kidney disease does not necessarily mean you will progress to advanced stages. Getting tested and understanding the stage of your kidney disease can help you work with your doctor to protect your kidney health.

Can kidney disease be reversed?

While there is no cure for kidney disease, and kidney damage cannot be reversed once it occurs, you can start taking steps now to slow the progression of kidney disease. Everyone experiences kidney disease differently. Many people who are diagnosed with kidney disease early never develop kidney failure, while those who develop kidney failure later can live healthy lives for decades with treatment, proper nutrition, and physical activity.